Product details
Background:
KCNIP4 rabbit pAb
Ucallm_WP7801-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | KCNIP4 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 28kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human KCNIP4 |
| Specificity | This antibody detects endogenous levels of KCNIP4 at Human, Mouse,Rat |
| Gene Name | KCNIP4 CALP KCHIP4 |
| Protein Name | Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel modulatory protein 4) (Calsenilin-like protein) (Potassium channel-interacting protein 4) |
| Other Name | |
| Species | Human |
| Gene ID | 80333 |
| Uniprot | Q6PIL6, |
| Species.1 | Mouse |
| Gene ID.1 | 80334 |
| Uniprot.1 | Q6PHZ8, |
| Species.2 | Rat |
| Gene ID.2 | 259243 |
| Uniprot.2 | Q99MG9 |
| Cellular Localization | Cell membrane; Peripheral membrane protein . Cytoplasm .; [Isoform 4]: Endoplasmic reticulum . |
| Tissue Expression | Predominantly expressed in brain. |
| Signaling_pathway | |
| Research Areas | |
| Function | Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Modulates KCND2 channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner . Modulates KCND3/Kv4.3 currents . Isoform 4 does not increase KCND2 expression at the cell membrane . Isoform 4 retains KCND3 in the endoplasmic reticulum and negatively regulates its expression at the cell membrane. |
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