SKU: WP1498 Categories: ,

KCNKG Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP1498-100
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Product details

Background:

potassium two pore domain channel subfamily K member 16(KCNK16) Homo sapiens The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. This gene is expressed predominantly in the pancreas and is activated at alkaline pH. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Sep 2008],

Specifications

Size50μL/100μL
TargetKCNKG
ReactivityHuman
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)33kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 230-310
SpecificityKCNKG Polyclonal Antibody detects endogenous levels of protein.
Gene NameKCNK16 TALK1
Protein NamePotassium channel subfamily K member 16 (2P domain potassium channel Talk-1) (TWIK-related alkaline pH-activated K(+) channel 1) (TALK-1)
Other Name
SpeciesHuman
Gene ID83795
UniprotQ96T55
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationMembrane; Multi-pass membrane protein.
Tissue ExpressionHighly expressed in pancreas. Not detectable in the other tissues tested.
Signaling_pathway
Research Areas
FunctionFunction:Outward rectifying potassium channel. Produces rapidly activating and non-inactivating outward rectifier K(+) currents.,miscellaneous:Inhibited by Ba(2+), quinine, quinidine, chloroform and halothane. Activated at alkaline pH.,similarity:Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.,subunit:Homodimer .,tissue specificity:Highly expressed in pancreas. Not detectable in the other tissues tested.,
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