Name: KDM4D Polyclonal Antibody
SKU: WP2059
Price: 268 USD
Availability: InStock

KDM4D Polyclonal Antibody

Ucallm_WP2059-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WP2059-100

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Product details

Background:

caution:It is uncertain whether Met-1 or Met-4 is the initiator., cofactor:Binds 1 Fe(2+) ion per subunit., function:Histone demethylase that specifically demethylates ‘Lys-9’ of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 ‘Lys-4’, H3 ‘Lys-27’, H3 ‘Lys-36’ nor H4 ‘Lys-20’. Demethylates both di- and trimethylated H3 ‘Lys-9’ residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate., similarity:Belongs to the JHDM3 histone demethylase family., similarity:Contains 1 JmjC domain., similarity:Contains 1 JmjN domain.,

Specifications

Size	50μL/100μL
Target	KDM4D
Reactivity	Human, Mouse, Rat
Applications	WB, ELISA
MW(Calculated)
MW(Observed)	57kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-2000; ELISA 1:5000-20000
Formulation	Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from human protein . at AA range: 400-480
Specificity	KDM4D Polyclonal Antibody detects endogenous levels of protein.
Gene Name	KDM4D JHDM3D JMJD2D
Protein Name	Lysine-specific demethylase 4D (JmjC domain-containing histone demethylation protein 3D) (Jumonji domain-containing protein 2D)
Other Name
Species	Human
Gene ID	55693
Uniprot	Q6B0I6,
Species.1	Mouse
Gene ID.1
Uniprot.1	Q3U2K5,
Species.2	Rat
Gene ID.2
Uniprot.2	A1A5Q5
Cellular Localization	Nucleus .
Tissue Expression	Brain,Embryo,Teratocarcinoma,Testis,
Signaling_pathway
Research Areas
Function	Caution:It is uncertain whether Met-1 or Met-4 is the initiator.,cofactor:Binds 1 Fe(2+) ion per subunit.,Function:Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate.,similarity:Belongs to the JHDM3 histone demethylase family.,similarity:Contains 1 JmjC domain.,similarity:Contains 1 JmjN domain.,