Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human KIF3A
Specificity
This antibody detects endogenous levels of KIF3A at Human, Mouse
Gene Name
KIF3A KIF3
Protein Name
Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A)
Other Name
Species
Human
Gene ID
11127
Uniprot
Q9Y496,
Species.1
Mouse
Gene ID.1
16568
Uniprot.1
P28741
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasm, cytoskeleton . Cell projection, cilium . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Localizes to the subdistal appendage region of the centriole. .
Tissue Expression
Signaling_pathway
Environmental Information Processing >> Signal transduction >> Hedgehog signaling pathway
Research Areas
Function
Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. Plays a role in primary cilia formation. Plays a role in centriole cohesion and subdistal appendage organization and function. Regulates the formation of the subdistal appendage via recruitment of DCTN1 to the centriole. Also required for ciliary basal feet formation and microtubule anchoring to mother centriole.