PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Contains 1 BTB (POZ) domain., similarity:Contains 6 Kelch repeats.,
Specifications
Size
50μL/100μL
Target
KLDC5
Reactivity
Human, Mouse
Applications
WB, ELISA
MW(Calculated)
MW(Observed)
55kD
Host Species
Rabbit
Isotype
IgG
Conjugate/Modification
Unmodified
Recommended Dilution Ratio
WB 1:500-2000; ELISA 1:5000-20000
Formulation
Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from part region of human protein
Specificity
KLDC5 Polyclonal Antibody detects endogenous levels of protein.
Gene Name
KLHDC5 KIAA1340
Protein Name
Kelch domain-containing protein 5
Other Name
Species
Human
Gene ID
57542
Uniprot
Q9P2K6,
Species.1
Mouse
Gene ID.1
Uniprot.1
Q8BFQ9
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasm . Cytoplasm, cytoskeleton, spindle . Predominantly in mitotic cells. Localized diffusely in the cytoplasm during the interphase. During metaphase is localized throughout the cell and more widely dispersed than the microtubules. In anaphase cells is localized between the two sets of separated chromosomes as well as at the spindle poles. During telophase is localized arround the nuclei of the two daughter cells. Not detected at the midbody region during cytokinesis.
Tissue Expression
Brain,Tongue,Uterus,
Signaling_pathway
Research Areas
Function
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 6 Kelch repeats.,