Price range: $268.00 through $328.00
Background:
This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor involved in the control of differentiation and development of the pituitary gland. Mutations in this gene cause combined pituitary hormone deficiency 4. [provided by RefSeq, Dec 2010],
| Size | 50μL/100μL |
| Target | LHX4 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 42kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 160-240 |
| Specificity | LHX4 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | LHX4 |
| Protein Name | LIM/homeobox protein Lhx4 (LIM homeobox protein 4) |
| Other Name | |
| Species | Human |
| Gene ID | 89884 |
| Uniprot | Q969G2, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P53776 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Muscle,Placenta, |
| Signaling_pathway | |
| Research Areas | |
| Function | Disease:A chromosomal aberration involving LHX4 may be a cause of acute lymphoblastic leukemia. Translocation t(1; 14)(q25; q32) with IGHG1.,Disease:Defects in LHX4 are the cause of Machinis syndrome [MIM:606606]. It is characterized by short stature, pituitary and cerebellar defects, and small sella turcica.,Function:May play a critical role in the development of respiratory control mechanisms and in the normal growth and maturation of the lung.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 1 LIM zinc-binding domain.,similarity:Contains 2 LIM zinc-binding domains., |
