Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human LRFN1 AA range: 529-579
Specificity
This antibody detects endogenous levels of LRFN1 at Human/Mouse/Rat
Gene Name
LRFN1 KIAA1484 SALM2
Protein Name
LRFN1
Other Name
Leucine-rich repeat and fibronectin type III domain-containing protein 1; / Synaptic adhesion-like molecule 2
Species
Human
Gene ID
57622
Uniprot
Q9P244,
Species.1
Mouse
Gene ID.1
80749
Uniprot.1
Q2WF71,
Species.2
Rat
Gene ID.2
365222
Uniprot.2
P0C7J6
Cellular Localization
Membrane; Single-pass type I membrane protein . Cell junction, synapse . Cell junction, synapse, postsynaptic density membrane . Detected in excitatory, but not inhibitory, synaptic plasma membrane. .
Tissue Expression
Brain,Ovary,Uterus,
Signaling_pathway
Research Areas
Function
Function:Involved in the regulation of excitatory synapses.,PTM:Glycosylated.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the LRFN family.,similarity:Contains 1 fibronectin type-III domain.,similarity:Contains 1 Ig-like (immunoglobulin-like) domain.,similarity:Contains 7 LRR (leucine-rich) repeats.,subunit:Interacts with DLG1, DLGAP1, AMPA receptors and NMDA receptors (By similarity). Interacts with DLG4.,