Price range: $268.00 through $328.00
Background:Predicted to enable acetylcholine receptor binding activity and acetylcholine receptor inhibitor activity. Predicted to be involved in acetylcholine receptor signaling pathway. Located in external side of plasma membrane. Is expressed in large intestine; small intestine; and spleen. [provided by Alliance of Genome Resources, Nov 2024]
| Size | 50μL/100μL |
| Target | Ly6g |
| Reactivity | Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | 14kD |
| MW(Observed) | 14kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:1000-1:4000; WB 1:1000-1:5000; IF 1:200-1:1000; ELISA 1:5000-1:20000; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM0473R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | Ly6g |
| Protein Name | Lymphocyte antigen 6G; Ly-6G; Ly-6G.1 |
| Other Name | Gr-1; / Gr1; / Ly-6G.1; / Ly6G; / Lymphocyte antigen 6 complex locus G; / Lymphocyte antigen 6G |
| Species | Mouse |
| Gene ID | 546644 |
| Uniprot | P35461 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Membrane |
| Tissue Expression | Expressed in bone marrow. |
| Signaling_pathway | |
| Research Areas | |
| Function | Ly6G is a GPI-anchored protein, that is also known as the myeloid differentiation antigen Gr1. The antigen is transiently expressed on monocytes in the bone marrow. The level of antigen expression in the bone marrow directly correlates with granulocyte differentiation and maturation. Ly6G is expressed predominantly on neutrophils, also in a subset of eosinophils, differentiating pre-monocytes, and plasmacytoid dendritic cells. |
