SKU: WP0687 Categories: ,

MAGE1 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP0687-100
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Product details

Background:

This gene encodes an alpha-dystrobrevin-associated MAGE (melanoma-associated antigen) protein, which is a member of the MAGE family. The protein contains a nuclear localization signal in the N-terminus, 30 12-amino acid repeats beginning at nt 60 with the consensus sequence ASEGPSTSVLPT, and two MAGE domains in the C-terminus. It may play a signaling role in brain, muscle, and peripheral nerve. This gene is located on X chromosome in a region containing loci linked to mental retardation. [provided by RefSeq, Mar 2010],

Specifications

Size50μL/100μL
TargetMAGE1
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)105kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 760-840
SpecificityMAGE1 Polyclonal Antibody detects endogenous levels of protein.
Gene NameMAGEE1 HCA1 KIAA1587
Protein NameMelanoma-associated antigen E1 (Alpha-dystrobrevin-associated MAGE Protein) (DAMAGE) (Hepatocellular carcinoma-associated protein 1) (MAGE-E1 antigen)
Other Name
SpeciesHuman
Gene ID57692
UniprotQ9HCI5,
Species.1Mouse
Gene ID.1
Uniprot.1Q6PCZ4,
Species.2Rat
Gene ID.2
Uniprot.2A1A5P9
Cellular LocalizationCytoplasm, perinuclear region . Nucleus . Cell membrane . In the skeletal muscle, found at the postsynaptic membrane and is associated with a subset of myonuclei. May reside within nuclei and/or in perinuclear compartments. In peripheral nerves, colocalizes with DTNA in the Schwann cell membrane (By similarity). .
Tissue ExpressionBrain,PNS,Testis,
Signaling_pathway
Research Areas
Functionsimilarity:Contains 2 MAGE domains.,
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