Price range: $268.00 through $328.00
Background:
function:Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas., PTM:May possess two intramolecular disulfide bonds., similarity:Belongs to the MIA/OTOR family., similarity:Contains 1 SH3 domain., tissue specificity:All malignant melanoma cell lines tested and infrequently in glioma cell lines.,
| Size | 50μL/100μL |
| Target | MIA |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:50-200; ELISA 1:10000-20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthetic peptide from human protein at AA range: 90-131 |
| Specificity | The antibody detects endogenous MIA |
| Gene Name | MIA |
| Protein Name | Melanoma-derived growth regulatory protein (Melanoma inhibitory activity protein) |
| Other Name | MIA; / Melanoma-derived growth regulatory protein; / Melanoma inhibitory activity protein |
| Species | Human |
| Gene ID | 8190 |
| Uniprot | Q16674, |
| Species.1 | Mouse |
| Gene ID.1 | 12587 |
| Uniprot.1 | Q61865, |
| Species.2 | Rat |
| Gene ID.2 | 81510 |
| Uniprot.2 | Q62946 |
| Cellular Localization | Secreted. |
| Tissue Expression | All malignant melanoma cell lines tested and infrequently in glioma cell lines. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas.,PTM:May possess two intramolecular disulfide bonds.,similarity:Belongs to the MIA/OTOR family.,similarity:Contains 1 SH3 domain.,tissue specificity:All malignant melanoma cell lines tested and infrequently in glioma cell lines., |
