Product details
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MIOS rabbit pAb
Ucallm_WP7386-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | MIOS |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 96kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human MIOS |
| Specificity | This antibody detects endogenous levels of MIOS at Human, Mouse |
| Gene Name | MIOS |
| Protein Name | WD repeat-containing protein mio |
| Other Name | |
| Species | Human |
| Gene ID | 54468 |
| Uniprot | Q9NXC5, |
| Species.1 | Mouse |
| Gene ID.1 | 252875 |
| Uniprot.1 | Q8VE19 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Lysosome membrane . |
| Tissue Expression | |
| Signaling_pathway | Environmental Information Processing >> Signal transduction >> mTOR signaling pathway |
| Research Areas | |
| Function | As a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex . It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 . |
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