SKU: WP13204 Categories: ,

MMP-23 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP13204-100
Enter the quantity you would like, or drag the panel to find the quantity and price that best for you
Bulk QuoteAuthorize OEM & ODM

Product details

Background:

This gene (MMP23B) encodes a member of the matrix metalloproteinase (MMP) family, and it is part of a duplicated region of chromosome 1p36.3. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. This gene belongs to the more telomeric copy of the duplicated region. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetMMP-23
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA, IHC
MW(Calculated)
MW(Observed)44kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human MMP-23. AA range:341-390
SpecificityMMP-23 Polyclonal Antibody detects endogenous levels of MMP-23 protein.
Gene NameMMP23B
Protein NameMatrix metalloproteinase-23
Other NameMMP23A; / MMP21; / MMP23B; / MMP21; / MMP22; / Matrix metalloproteinase-23; / MMP-23; / Femalysin; / MIFR-1; / Matrix metalloproteinase-21; / MMP-21; / Matrix metalloproteinase-22; / MMP-22
SpeciesHuman
Gene ID8510
UniprotO75900,
Species.1Mouse
Gene ID.126561
Uniprot.1O88676,
Species.2Rat
Gene ID.294339
Uniprot.2O88272
Cellular LocalizationEndoplasmic reticulum membrane; Single-pass type II membrane protein . Membrane; Single-pass type II membrane protein . A secreted form produced by proteolytic cleavage may also exist. .
Tissue ExpressionPredominantly expressed in ovary, testis and prostate.
Signaling_pathway
Research Areas
Functioncofactor:Binds 1 zinc ion per subunit.,enzyme regulation:Inhibited by TIMP2.,Function:Protease.,PTM:N-glycosylated.,PTM:Proteolytic cleavage might yield an active form.,similarity:Belongs to the peptidase M10A family.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,subcellular location:A secreted form produced by proteolytic cleavage seems also to exist.,tissue specificity:Predominantly expressed in ovary, testis and prostate.,
Please login to post questions
Back to Top
Product has been added to your cart