Product details
Background:
This gene encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells.
Nestin Mouse mAb [PTR1402]
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Price range: $268.00 through $328.00
Specifications
| Target | Nestin |
| Reactivity | Human |
| Applications | WB, IHC, IF, IP, ELISA |
| MW(Calculated) | 177kD |
| MW(Observed) | 220kD |
| Host Species | Mouse |
| Isotype | IgG1,kappa |
| Conjugate/Modification | Unmodified |
| Modification | |
| Recommended Dilution Ratio | IHC 1:100-500; WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Source | |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein G affinity chromatography. |
| Purity | |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | PTR1402 |
| Immunogen | AA range 1500-1621 |
| Sequence | |
| Specificity | Endogenous |
| Gene Name | NES Nbla00170 |
| Protein Name | Nestin |
| Other Name | |
| Species | Human |
| Gene ID-1 | 10763 |
| Uniprot | P48681, |
| Species.1 | Mouse |
| Gene ID-2 | |
| Uniprot.1 | Q6P5H2, |
| Species.2 | Rat |
| Gene ID-3 | |
| Uniprot.2 | P21263 |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Background | This gene encodes a member of the intermediate filament protein family and is expressed primarily in nerve cells. [provided by RefSeq, Sep 2011], |
| Cellular Localization | Cytoplasm |
| Tissue Expression | CNS stem cells. |
| Signaling_pathway | |
| Research Areas | |
| Function | developmental stage:Upon terminal neural differentiation, nestin is down-regulated and replaced by neurofilaments.,Function:May play a role in the trafficking and distribution of IF proteins and potentially other cellular factors to daughter cells during progenitor cell division.,similarity:Belongs to the intermediate filament family.,subunit:Interacts with FHOD3.,tissue specificity:CNS stem cells., |
| RRID |
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