PDGFR α [PTR1303] mouse mAb
Ucallm_WM1343-50
Price range: $268.00 through $328.00
Product details
Background:
platelet derived growth factor receptor alpha(PDGFRA) Homo sapiens This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012],
Specifications
| Size | 50μL/100μL |
| Target | PDGFRA |
| Reactivity | Human,Mouse,Rat, |
| Applications | WB,IF,ELISA |
| MW(Calculated) | 175kD |
| MW(Observed) | 190kD |
| Host Species | Mouse |
| Isotype | IgG1,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000;IF 1:100-500;ELISA 1:1000-5000 |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Protein G |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Monoclonal |
| Clone Number | RMMR1303 |
| Immunogen | Synthesized peptide derived from human PDGFR α. AA range: 300-400 |
| Specificity | This antibody detects endogenous levels of PDGFR α protein. |
| Gene Name | PDGFRA PDGFR2 RHEPDGFRA |
| Protein Name | Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a) |
| Other Name | Platelet-derived growth factor receptor alpha;PDGF-R-alpha;PDGFR-alpha;Alpha platelet-derived growth factor receptor;Alpha-type platelet-derived growth factor receptor;CD140 antigen-like family member A;CD140a antigen;Platelet-derived growth factor alpha receptor;Platelet-derived growth factor receptor 2;PDGFR-2;CD antigen CD140a; |
| Species | Human |
| Gene ID | 5156 |
| Uniprot | P16234 |
| Species.1 | Mouse |
| Gene ID.1 | 18595 |
| Uniprot.1 | P26618 |
| Species.2 | Rat |
| Gene ID.2 | 25267 |
| Uniprot.2 | P20786 |
| Cellular Localization | Membranous |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function |
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