Price range: $268.00 through $328.00
Background:
Protein phosphatase-1 (PP1; see MIM 176875) interacts with regulatory subunits that target the enzyme to different cellular locations and change its activity toward specific substrates. Phostensin is a regulatory subunit that targets PP1 to F-actin (see MIM 102610) cytoskeleton (Kao et al., 2007 [PubMed 17374523]).[supplied by OMIM, Mar 2008],
| Size | 50μL/100μL |
| Target | Phostensin |
| Reactivity | Human |
| Applications | WB |
| MW(Calculated) | |
| MW(Observed) | 120kD |
| Host Species | Mouse |
| Isotype | |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:200 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | 17A2 |
| Immunogen | Purified recombinant human Phostensin protein fragments expressed in E.coli. |
| Specificity | This antibody detects endogenous levels of Phostensin and does not cross-react with related proteins. |
| Gene Name | ppp1r18 |
| Protein Name | |
| Other Name | HKMT1098; / KIAA1949; / Protein phosphatase 1 F actin cytoskeleton targeting subunit. |
| Species | Human |
| Gene ID | 170954 |
| Uniprot | Q6NYC8, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q8BQ30 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | [Isoform 1]: Cytoplasm, cytoskeleton .; [Isoform 4]: Cytoplasm, cytoskeleton . |
| Tissue Expression | Isoform 4 is predominantly expressed in leukocytes and spleen. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:May target protein phosphatase 1 to F-actin cytoskeleton.,subunit:Interacts with Protein phosphatase 1 (PP1).,tissue specificity:Predominantly expressed in leukocytes and spleen., |
