Price range: $268.00 through $328.00
Background:
PSA is a glycoprotein synthesized by prostate epithelial cells. It is expressed in normal prostate acinar cells, ductal epithelial cells and intraluminal secretions. It is one of the specific prostate markers. It is mainly used for the diagnosis of prostate cancer and metastatic prostate cancer.
| Size | 50μL/100μL |
| Target | PSA |
| Reactivity | Human |
| Applications | IHC, WB, IF, ELISA |
| MW(Calculated) | 28kD |
| MW(Observed) | 28kD |
| Host Species | Mouse |
| Isotype | IgG1,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:200-1000; WB 1:500-2000; IF 1:100-500; ELISA 1:1000-5000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein G affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RMM-PSA |
| Immunogen | Synthesized peptide derived from human Prostate-Specific Antigen(PSA) AA range: 100-200 |
| Specificity | The antibody can specifically recognize human PSA protein. |
| Gene Name | KLK3 APS |
| Protein Name | Prostate-specific antigen (PSA) (Gamma-seminoprotein) (Seminin) (Kallikrein-3) (P-30 antigen) (Semenogelase) |
| Other Name | antigen, prostate-specific; / APS; / Gamma seminoprotein; / Gamma-seminoprotein; / hK3; / Kallikrein 3; / Kallikrein related peptidase 3; / Kallikrein-3; / KLK 3; / KLK2A1; / Klk3; / KLK3_HUMAN; / P-30 antigen; / P30 antigen; / Prostate-specific antigen; / Psa; / Semenogelase; / Seminin |
| Species | Human |
| Gene ID | 354 |
| Uniprot | P07288 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasmic |
| Tissue Expression | Leukocyte,PNS,Prostate, |
| Signaling_pathway | Human Diseases >> Cancer: overview >> Pathways in cancer;Human Diseases >> Cancer: specific types >> Prostate cancer |
| Research Areas | >>Pathways in cancer; / >>Prostate cancer |
| Function | Catalytic activity:Preferential cleavage: -Tyr-|-Xaa-.,Function:Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.,online information:Prostate-specific antigen entry,similarity:Belongs to the peptidase S1 family.,similarity:Belongs to the peptidase S1 family. Kallikrein subfamily.,similarity:Contains 1 peptidase S1 domain., |
