Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human RBM11
Specificity
This antibody detects endogenous levels of RBM11 at Human, Mouse
Gene Name
RBM11
Protein Name
Splicing regulator RBM11 (RNA-binding motif protein 11)
Other Name
Species
Human
Gene ID
54033
Uniprot
P57052,
Species.1
Mouse
Gene ID.1
224344
Uniprot.1
Q80YT9
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Nucleus, nucleoplasm . Nucleus speckle . Enriched in SRSF2-containing splicing speckles; shuttles between nucleoplasm and speckles.
Tissue Expression
Expressed in brain, hippocampus, prefrontal cortex, cerebellum, spinal cord, testis, mammary gland, spleen and kidney. Also expressed in fetal brain.
Signaling_pathway
Research Areas
Function
Tissue-specific splicing factor with potential implication in the regulation of alternative splicing during neuron and germ cell differentiation. Antagonizes SRSF1-mediated BCL-X splicing. May affect the choice of alternative 5' splice sites by binding to specific sequences in exons and antagonizing the SR protein SRSF1.