SKU: WP17190 Categories: ,

RBM25 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP17190-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetRBM25
ReactivityHuman, Mouse
ApplicationsWB, IHC
MW(Calculated)93kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; IHC 1:50-300 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human RBM25 AA range: 763-813
SpecificityThis antibody detects endogenous levels of RBM25 at Human/Mouse
Gene NameRBM25 RNPC7
Protein NameRBM25
Other Name
SpeciesHuman
Gene ID58517
UniprotP49756,
Species.1Mouse
Gene ID.167039
Uniprot.1B2RY56
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus speckle. Cytoplasm. Colocalizes predominantly, with SFRS2 and LUC7L3 splicing factors, in nuclear speckles. Cytoplasmic localization is faint.
Tissue Expression
Signaling_pathway
Research Areas>>Spliceosome
FunctionPTM:Sumoylated.,sequence Caution:Contaminating sequence. Potential poly-A sequence.,sequence Caution:Translation N-terminally extended.,similarity:Contains 1 PWI domain.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subcellular location:Detected predominantly in nuclear speckles. Cytoplasmic localization is faint.,subunit:Interacts with SRRM1. Specifically associates with functional splicing complexes, including Sm proteins and U1, U2, U4, U5 and U6 snRNAs. Associates with exon junction complex (EJC) proteins, including APEX1, BAT1, NCBP1, RBM8A and RNPS1. Interaction with NCBP1 is RNA-dependent.,
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