SKU: WP3356 Categories: ,

RBMS1 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP3356-100
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Product details

Background:

This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12. [provided by RefSeq, Feb 2009],

Specifications

Size50μL/100μL
TargetRBMS1
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)44kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from part region of human protein
SpecificityRBMS1 Polyclonal Antibody detects endogenous levels of protein.
Gene NameRBMS1 C2orf12 MSSP MSSP1 SCR2
Protein NameRNA-binding motif, single-stranded-interacting protein 1 (Single-stranded DNA-binding protein MSSP-1) (Suppressor of CDC2 with RNA-binding motif 2)
Other Name
SpeciesHuman
Gene ID5937
UniprotP29558,
Species.1Mouse
Gene ID.1
Uniprot.1Q91W59,
Species.2Rat
Gene ID.2
Uniprot.2Q5PQP1
Cellular LocalizationNucleus.
Tissue ExpressionHighest amounts are found in placenta, lung and heart.
Signaling_pathway
Research Areas
Functiondevelopmental stage:Expressed at highest levels during the G1 to S transition of the cell cycle.,Function:Single-stranded DNA binding protein that interacts with the region upstream of the C-myc gene. Binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA replication.,sequence Caution:Translation N-terminally extended.,similarity:Contains 2 RRM (RNA recognition motif) domains.,tissue specificity:Highest amounts are found in placenta, lung and heart.,
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