SKU: WN0564 Categories: ,

Recombinant CD9 Fc-Fused Nanobody (VF0192)

$365.00

SKU: WN0564
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Product details

Background:This gene encodes a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression ofThis gene plays a critical role in the suppression of cancer cell motility and metastasis. [provided by RefSeq, Jan 2011]

Specifications

Size100μL
TargetCD9
ReactivityHuman
ApplicationsELISA
MW(Calculated)
MW(Observed)
Host Species
IsotypeIgG2a,Kappa
Conjugate/ModificationUnmodified
Recommended Dilution RatioELISA 1:5000-100000
FormulationPhosphate-buffered solution
PurificationRecombinant Expression and Affinity purified
Storage-15°C to -25°C/1 year(Avoid freeze / thaw cycles)
ConcentrationPlease check the information on the tube
Clonality
Clone NumberVF0233
ImmunogenPurified recombinant Human CD9
SpecificityThis recombinant monoclonal antibody can detects endogenous levels of CD9 protein.
Gene NameCD9 MIC3 TSPAN29 GIG2
Protein NameCD9 antigen (5H9 antigen) (Cell growth-inhibiting gene 2 protein) (Leukocyte antigen MIC3) (Motility-related protein) (MRP-1) (Tetraspanin-29) (Tspan-29) (p24) (CD antigen CD9)
Other NameCD9; / MIC3; / TSPAN29; / GIG2; / CD9 antigen; / 5H9 antigen; / Cell growth-inhibiting gene 2 protein; / Leukocyte antigen MIC3; / Motility-related protein; / MRP-1; / Tetraspanin-29; / Tspan-29; / p24; / CD antigen CD9; / CD9 nanobody
SpeciesHuman
Gene ID928
UniprotP21926
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCell membrane; Multi-pass membrane protein . Membrane; Multi-pass membrane protein . Secreted, extracellular exosome . Present at the cell surface of oocytes. Accumulates in the adhesion area between the sperm and egg following interaction between IZUMO1 and its receptor IZUMO1R/JUNO. .
Tissue Expression
Signaling_pathwayOrganismal Systems >> Immune system >> Hematopoietic cell lineage
Research Areas
FunctionInvolved in platelet activation and aggregation. Regulates paranodal junction formation. Involved in cell adhesion, cell motility and tumor metastasis. Required for sperm-egg fusion.,PTM:Protein exists in three forms with molecular masses between 22 and 27 kDa, and is known to carry covalently linked fatty acids.,similarity:Belongs to the tetraspanin (TM4SF) family.,subunit:Forms both disulfide-linked homodimers and higher homooligomers as well as heterooligomers with other members of the tetraspanin family. Associates with CR2/CD21 and with PTGFRN/CD9P1. Interacts directly with IGSF8.,tissue specificity:Expressed by a variety of hematopoietic and epithelial cells.,
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