Product details
Background:The protein encoded byThis gene is a pleiotropic cytokine produced by activated T cells.This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions ofThis cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal ofThis cytokine.This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, withThis gene particularly close to IL13.This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants ofThis gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
