Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human RGS9
Specificity
This antibody detects endogenous levels of RGS9 at Human, Mouse,Rat
Gene Name
RGS9
Protein Name
Regulator of G-protein signaling 9 (RGS9)
Other Name
Species
Human
Gene ID
8787
Uniprot
O75916,
Species.1
Mouse
Gene ID.1
19739
Uniprot.1
O54828,
Species.2
Rat
Gene ID.2
29481
Uniprot.2
P49805
Cellular Localization
[Isoform 3]: Membrane; Peripheral membrane protein. Isoform 3 is targeted to the membrane via its interaction with RGS9BP. .
Tissue Expression
Highly expressed in the caudate and putamen, lower levels found in the hypothalamus and nucleus accumbens and very low levels in cerebellum. Not expressed in globus pallidus or cingulate cortex. Isoform 2 is expressed predominantly in pineal gland and retina. Isoform 3 is expressed in retina (abundant in photoreceptors).
Signaling_pathway
Research Areas
Function
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to GNAT1. Involved in phototransduction; key element in the recovery phase of visual transduction (By similarity).