Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human RHBDF2
Specificity
This antibody detects endogenous levels of RHBDF2 at Human, Mouse
Gene Name
RHBDF2 IRHOM2 RHBDL5 RHBDL6
Protein Name
Inactive rhomboid protein 2 (iRhom2) (Rhomboid 5 homolog 2) (Rhomboid family member 2) (Rhomboid veinlet-like protein 5) (Rhomboid veinlet-like protein 6)
Other Name
Species
Human
Gene ID
79651
Uniprot
Q6PJF5,
Species.1
Mouse
Gene ID.1
217344
Uniprot.1
Q80WQ6
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Endoplasmic reticulum membrane; Multi-pass membrane protein . Cell membrane .
Tissue Expression
Found in the epidermis and esophageal epithelium.
Signaling_pathway
Research Areas
Function
Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.