Price range: $268.00 through $328.00
Background:
function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Acts as a GTPase activitor in vitro for CDC42 and RAC1., sequence caution:Translation N-terminally extended., similarity:Contains 1 BAR domain., similarity:Contains 1 Rho-GAP domain., tissue specificity:Highly expressed in brain. Expressed at weak level in other tissues.,
| Size | 50μL/100μL |
| Target | RHG44 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 89kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 430-510 |
| Specificity | RHG44 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | ARHGAP44 KIAA0672 RICH2 |
| Protein Name | Rho GTPase-activating protein 44 (NPC-A-10) (Rho-type GTPase-activating protein RICH2) (RhoGAP interacting with CIP4 homologs protein 2) (RICH-2) |
| Other Name | |
| Species | Human |
| Gene ID | 9912 |
| Uniprot | Q17R89, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q5SSM3 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell projection, dendritic spine . Recycling endosome . Cell junction, synapse, presynapse . Cell projection, dendrite . In CA1 hippocampal synapses, detected at both presynaptic and postsynaptic sites (By similarity). Located in convoluted dendritic plasma membrane sections enriched in polymerized actin and myosin (patches) along dendrites where often emerge filopodia (By similarity). . |
| Tissue Expression | Highly expressed in brain. Expressed at weak level in other tissues. |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Acts as a GTPase activitor in vitro for CDC42 and RAC1.,sequence Caution:Translation N-terminally extended.,similarity:Contains 1 BAR domain.,similarity:Contains 1 Rho-GAP domain.,tissue specificity:Highly expressed in brain. Expressed at weak level in other tissues., |
