Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human RHOC
Specificity
This antibody detects endogenous levels of RHOC at Human, Mouse
Gene Name
RHOC ARH9 ARHC
Protein Name
Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9)
Other Name
Species
Human
Gene ID
389
Uniprot
P08134,
Species.1
Mouse
Gene ID.1
11853
Uniprot.1
Q62159
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cell membrane; Lipid-anchor; Cytoplasmic side . Cleavage furrow . Translocates to the equatorial region before furrow formation in a ECT2-dependent manner.
Tissue Expression
Signaling_pathway
Research Areas
Function
Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells.