RHOC rabbit pAb
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | Rho C |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 21kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human RHOC |
| Specificity | This antibody detects endogenous levels of RHOC at Human, Mouse |
| Gene Name | RHOC ARH9 ARHC |
| Protein Name | Rho-related GTP-binding protein RhoC (Rho cDNA clone 9) (h9) |
| Other Name | |
| Species | Human |
| Gene ID | 389 |
| Uniprot | P08134, |
| Species.1 | Mouse |
| Gene ID.1 | 11853 |
| Uniprot.1 | Q62159 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane; Lipid-anchor; Cytoplasmic side . Cleavage furrow . Translocates to the equatorial region before furrow formation in a ECT2-dependent manner. |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Regulates apical junction formation in bronchial epithelial cells. |
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