SKU: WP14322 Categories: ,

Ribosomal Protein S12 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP14322-100
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Product details

Background:

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S12E family of ribosomal proteins. It is located in the cytoplasm. Increased expression of this gene in colorectal cancers compared to matched normal colonic mucosa has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetRibosomal Protein S12
ReactivityHuman, Mouse, Rat
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)15kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human RPS12. AA range:83-132
SpecificityRibosomal Protein S12 Polyclonal Antibody detects endogenous levels of Ribosomal Protein S12 protein.
Gene NameRPS12
Protein Name40S ribosomal protein S12
Other NameRPS12; / 40S ribosomal protein S12
SpeciesHuman
Gene ID6206
UniprotP25398,
Species.1Mouse
Gene ID.1
Uniprot.1P63323,
Species.2Rat
Gene ID.2
Uniprot.2P63324
Cellular LocalizationCytoplasm.
Tissue ExpressionCervix carcinoma,Embryonic stem cell,Hepatoma,Mammary carcinoma,Placenta,Skin,Testi
Signaling_pathway
Research Areas>>Ribosome; / >>Coronavirus disease - COVID-19
Functionsimilarity:Belongs to the ribosomal protein S12e family.,
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