Product details
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RIM2 rabbit pAb
Ucallm_WP8591-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | RIMS2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 155kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human RIM2 |
| Specificity | This antibody detects endogenous levels of RIM2 at Human, Mouse,Rat |
| Gene Name | RIMS2 KIAA0751 RAB3IP3 RIM2 |
| Protein Name | Regulating synaptic membrane exocytosis protein 2 (Rab-3-interacting molecule 2) (RIM 2) (Rab-3-interacting protein 3) |
| Other Name | |
| Species | Human |
| Gene ID | 9699 |
| Uniprot | Q9UQ26, |
| Species.1 | Mouse |
| Gene ID.1 | 116838 |
| Uniprot.1 | Q9EQZ7, |
| Species.2 | Rat |
| Gene ID.2 | 116839 |
| Uniprot.2 | Q9JIS1 |
| Cellular Localization | Cell membrane; Peripheral membrane protein . Cell junction, synapse . Cell junction, synapse, presynaptic cell membrane; Peripheral membrane protein . |
| Tissue Expression | Widely expressed (PubMed:32470375). Expressed in melanocytes (PubMed:23999003). In fetal tissues, predominantly expressed in the brain (PubMed:32470375). In the retina, expressed in the outer plexiform layer (at protein level) (PubMed:32470375). In the cerebellum, expressed in Purkinje cells (at protein level) (PubMed:32470375). In the pancreas, expressed in Langerhans islets (at protein level) (PubMed:32470375). |
| Signaling_pathway | Organismal Systems >> Endocrine system >> Insulin secretion |
| Research Areas | |
| Function | Rab effector involved in exocytosis. May act as scaffold protein. Plays a role in dendrite formation by melanocytes . |
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