Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human RNASEH1
Specificity
This antibody detects endogenous levels of RNASEH1 at Human,Rat
Gene Name
RNASEH1 RNH1
Protein Name
Ribonuclease H1 (RNase H1) (Ribonuclease H type II)
Other Name
Species
Human
Gene ID
246243
Uniprot
O60930,
Species.1
Mouse
Gene ID.1
Uniprot.1
O70338,
Species.2
Rat
Gene ID.2
298933
Uniprot.2
Q5BK46
Cellular Localization
Cytoplasm .
Tissue Expression
Ubiquitous.
Signaling_pathway
Research Areas
Function
Endonuclease that specifically degrades the RNA of RNA-DNA hybrids . Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II .