Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human RNASEH2C
Specificity
This antibody detects endogenous levels of RNASEH2C at Human, Mouse
Gene Name
RNASEH2C AYP1
Protein Name
Ribonuclease H2 subunit C (RNase H2 subunit C) (Aicardi-Goutieres syndrome 3 protein) (AGS3) (RNase H1 small subunit) (Ribonuclease HI subunit C)
Other Name
Species
Human
Gene ID
84153
Uniprot
Q8TDP1,
Species.1
Mouse
Gene ID.1
68209
Uniprot.1
Q9CQ18
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Nucleus .
Tissue Expression
Widely expressed.
Signaling_pathway
Research Areas
Function
Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes.