Name: RPA32/RPA2 mouse mAb
SKU: WM0694
Price: 268 USD
Availability: InStock

RPA32/RPA2 mouse mAb

Ucallm_WM0694-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WM0694-50

Enter the quantity you would like, or drag the panel to find the quantity and price that best for you

Bulk Quote Authorize OEM & ODM

Product details

Background:
function:Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions., PTM:Phosphorylated in a cell-cycle-dependent manner (from the S phase until mitosis). Phosphorylated by ATR upon DNA damage, which promotes its translocation to nuclear foci. Can be phosphorylated in vitro by PRKDC/DNA-PK in the presence of Ku and DNA, and by CDC2., subcellular location:Also present in PML nuclear bodies. Redistributes to discrete nuclear foci upon DNA damage., subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Binds to SERTAD3/RBT1. Interacts with TIPIN.,

Specifications

Size	50μL/100μL
Target	RPA2
Reactivity	Human
Applications	WB, IP, ICC
MW(Calculated)
MW(Observed)	32kD
Host Species	Mouse
Isotype
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:2000; ICC 1:200
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Clonality	Monoclonal
Clone Number	6H4
Immunogen	Purified recombinant human RPA32/RPA2 protein fragments expressed in E.coli.
Specificity	This antibody detects endogenous levels of RPA32/RPA2 and does not cross-react with related proteins.
Gene Name	rpa2
Protein Name
Other Name	60S acidic ribosomal protein P1; / AA409079; / AI325195; / AU020965; / HSSB; / ik:tdsubc_2g1; / M; / 2; / 21C; / MGC137236; / OTTHUMP00000004008; / p32; / p34; / RCJMB04_6d17 replication protein A2, 32kDa; / REPA 2; / REPA1; / REPA2; / Replication factor A protein 2; / Replication protein A 32 kDa subunit; / Replication protein A 32kDa subunit; / Replication protein A 34 kDa subunit; / Replication protein A; / replication protein A1; / 70kD; / Replication Protein A2; / 32kDa; / Replication protein A2 32kD; / Replication protein A2 32kDa; / Replication protein A2; / Replication protein A2, 32kDa; / RF A; / RF-A protein 2; / Rf-A2; / RFA; / RFA2_HUMAN; / RP A; / RP-A p32; / RP-A p34; / RP21C; / RPA 2; / RPA 32; / RPA; / RPA2; / RPA32; / RPA34; / RPA70; / RpLP1; / RpP2; / xx:tdsubc_2g1; / zgc:109822.
Species	Human
Gene ID	6118
Uniprot	P15927,
Species.1	Mouse
Gene ID.1
Uniprot.1	Q62193
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Nucleus . Nucleus, PML body . Redistributes to discrete nuclear foci upon DNA damage in an ATR-dependent manner. .
Tissue Expression	Kidney,Lung,Muscle,
Signaling_pathway
Research Areas	>>DNA replication; / >>Nucleotide excision repair; / >>Mismatch repair; / >>Homologous recombination; / >>Fanconi anemia pathway
Function	Function:Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.,PTM:Phosphorylated in a cell-cycle-dependent manner (from the S phase until mitosis). Phosphorylated by ATR upon DNA damage, which promotes its translocation to nuclear foci. Can be phosphorylated in vitro by PRKDC/DNA-PK in the presence of Ku and DNA, and by CDC2.,subcellular location:Also present in PML nuclear bodies. Redistributes to discrete nuclear foci upon DNA damage.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Binds to SERTAD3/RBT1. Interacts with TIPIN.,