SKU: WP4609 Categories: ,

RSLBA rabbit pAb

Price range: $268.00 through $328.00

SKU: WP4609-100
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Product details

Background:

RASL11A is a member of the small GTPase protein family with a high degree of similarity to RAS (see HRAS, MIM 190020) proteins.[supplied by OMIM, Nov 2008],

Specifications

Size50μL/100μL
TargetRSLBA
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)27kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human RSLBA AA range: 68-118
SpecificityThis antibody detects endogenous levels of RSLBA at Human/Mouse/Rat
Gene NameRASL11A
Protein NameRSLBA
Other Name
SpeciesHuman
Gene ID387496
UniprotQ6T310,
Species.1Mouse
Gene ID.168895
Uniprot.1Q6IMB1,
Species.2Rat
Gene ID.2304268
Uniprot.2Q6IMA3
Cellular LocalizationNucleus, nucleolus . Associates with rDNA transcription unit throughout the cell cycle. .
Tissue ExpressionWidely expressed. Down-regulated in prostate tumors compared to normal prostate tissue. High levels found in colon tumor and normal colon tissue followed by small intestine, liver, jejunum, ileum, bladder and aorta. Lowest levels observed in endothelial cells.
Signaling_pathway
Research Areas
Functiondevelopmental stage:Down-regulated during development of THP-1 monocytes into macrophages.,induction:Down-regulated by TGFB1.,similarity:Belongs to the small GTPase superfamily. Ras family.,tissue specificity:Widely expressed. Down-regulated in prostate tumors compared to normal prostate tissue. High levels found in colon tumor and normal colon tissue followed by small intestine, liver, jejunum, ileum, bladder and aorta. Lowest levels observed in endothelial cells.,
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