RASL11A is a member of the small GTPase protein family with a high degree of similarity to RAS (see HRAS, MIM 190020) proteins.[supplied by OMIM, Nov 2008],
Specifications
Size
50μL/100μL
Target
RSLBA
Reactivity
Human, Mouse, Rat
Applications
WB
MW(Calculated)
27kD
MW(Observed)
Host Species
Rabbit
Isotype
IgG
Conjugate/Modification
Unmodified
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human RSLBA AA range: 68-118
Specificity
This antibody detects endogenous levels of RSLBA at Human/Mouse/Rat
Gene Name
RASL11A
Protein Name
RSLBA
Other Name
Species
Human
Gene ID
387496
Uniprot
Q6T310,
Species.1
Mouse
Gene ID.1
68895
Uniprot.1
Q6IMB1,
Species.2
Rat
Gene ID.2
304268
Uniprot.2
Q6IMA3
Cellular Localization
Nucleus, nucleolus . Associates with rDNA transcription unit throughout the cell cycle. .
Tissue Expression
Widely expressed. Down-regulated in prostate tumors compared to normal prostate tissue. High levels found in colon tumor and normal colon tissue followed by small intestine, liver, jejunum, ileum, bladder and aorta. Lowest levels observed in endothelial cells.
Signaling_pathway
Research Areas
Function
developmental stage:Down-regulated during development of THP-1 monocytes into macrophages.,induction:Down-regulated by TGFB1.,similarity:Belongs to the small GTPase superfamily. Ras family.,tissue specificity:Widely expressed. Down-regulated in prostate tumors compared to normal prostate tissue. High levels found in colon tumor and normal colon tissue followed by small intestine, liver, jejunum, ileum, bladder and aorta. Lowest levels observed in endothelial cells.,