Product details
Background:
S43A3 rabbit pAb
Ucallm_WP17914-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | SLC43A3 |
| Reactivity | Human, Mouse |
| Applications | IHC, WB |
| MW(Calculated) | 54kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IHC 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human C-ternal S43A3 |
| Specificity | This antibody detects endogenous levels of S43A3 at Human, Mouse |
| Gene Name | SLC43A3 PSEC0252 |
| Protein Name | Solute carrier family 43 member 3 (Protein FOAP-13) |
| Other Name | Solute carrier family 43 member 3; / Protein FOAP-13 |
| Species | Human |
| Gene ID | 29015 |
| Uniprot | Q8NBI5, |
| Species.1 | Mouse |
| Gene ID.1 | 58207 |
| Uniprot.1 | A2AVZ9 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Basolateral cell membrane; Multi-pass membrane protein . |
| Tissue Expression | Widely expressed with highest levels in the liver and lung, followed by the pancreas (PubMed:26455426). Highly expressed in macrophages (Ref.1). |
| Signaling_pathway | |
| Research Areas | |
| Function | Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobases such as adenine, guanine and hypoxanthine . May regulate fatty acid (FA) transport in adipocytes, acting as a positive regulator of FA efflux and as a negative regulator of FA uptake (By similarity).; [Isoform 1]: Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobase adenine . Mediates the influx and efflux of the purine nucleobase analog drug 6-mercaptopurine across the membrane .; [Isoform 2]: Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobase adenine . Mediates the influx and efflux of the purine nucleobase analog drug 6-mercaptopurine across the membrane . |
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