SNX17 rabbit pAb
Ucallm_WP16835-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a B41 domain. This protein interacts with the cytoplasmic domain of P-selectin, and may function in the intracellular trafficking of P-selectin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2012],
Specifications
| Size | 50μL/100μL |
| Target | SNX17 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| MW(Calculated) | 52kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IHC 1:50-300 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human SNX17 AA range: 398-448 |
| Specificity | This antibody detects endogenous levels of SNX17 at Human/Mouse/Rat |
| Gene Name | SNX17 KIAA0064 |
| Protein Name | SNX17 |
| Other Name | |
| Species | Human |
| Gene ID | 9784 |
| Uniprot | Q15036, |
| Species.1 | Mouse |
| Gene ID.1 | 266781 |
| Uniprot.1 | Q8BVL3, |
| Species.2 | Rat |
| Gene ID.2 | 298836 |
| Uniprot.2 | Q6AYS6 |
| Cellular Localization | Cytoplasm . Early endosome . Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Domain:The PX domain is required for association with endosomes.,Function:May be involved in protein trafficking.,similarity:Belongs to the sorting nexin family.,similarity:Contains 1 PX (phox homology) domain.,similarity:Contains 1 Ras-associating domain.,subcellular location:Associated with early endosomes.,subunit:Interacts with the C-termini of P-selectin, PTC, LDLR, VLDLR, LRP1 and LRP8., |
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