SOX4 Polyclonal Antibody
Ucallm_WP2247-50
Price range: $268.00 through $328.00
Product details
Background:
SRY-box 4(SOX4) Homo sapiens This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | SOX4 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 52kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | SOX4 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | SOX4 |
| Protein Name | Transcription factor SOX-4 |
| Other Name | |
| Species | Human |
| Gene ID | 6659 |
| Uniprot | Q06945, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q06831 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Testis, brain, and heart. |
| Signaling_pathway | Human Diseases >> Cancer: overview >> MicroRNAs in cancer |
| Research Areas | >>MicroRNAs in cancer |
| Function | Function:Transcriptional activator that binds with high affinity to the T-cell enhancer motif 5'-AACAAAG-3' motif.,similarity:Contains 1 HMG box DNA-binding domain.,subunit:Interacts with UBE2I.,tissue specificity:Testis, brain, and heart., |
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