Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human SPACA3
Specificity
This antibody detects endogenous levels of SPACA3 at Human, Mouse
Gene Name
SPACA3 LYC3 LYZL3 SLLP1 SPRASA UNQ424/PRO862
Protein Name
Sperm acrosome membrane-associated protein 3 (Cancer/testis antigen 54) (CT54) (Lysozyme-like acrosomal sperm-specific secretory protein ALLP-17) (Lysozyme-like protein 3) (Sperm lysozyme-like protein 1) (Sperm protein reactive with antisperm antibodies) (Sperm protein reactive with ASA) [Cleaved into: Sperm acrosome membrane-associated protein 3, membrane form; Sperm acrosome membrane-associated protein 3, processed form]
Other Name
Species
Human
Gene ID
124912
Uniprot
Q8IXA5,
Species.1
Mouse
Gene ID.1
75622
Uniprot.1
Q9D9X8
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
[Isoform 1]: Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Single-pass type II membrane protein . Anterior acrosome in non-capacitated spermatozoa and retained in the equatorial segment and in the luminal face of both the inner and outer acrosomal membranes following capacitation and the acrosome reaction. .; [Isoform 2]: Secreted .
Tissue Expression
The processed form is expressed in sperm (at protein level). Expressed in testis, epididymis and placenta.
Signaling_pathway
Research Areas
Function
Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro.