Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human SPCS2
Specificity
This antibody detects endogenous levels of SPCS2 at Human, Mouse
Gene Name
SPCS2 KIAA0102 SPC25
Protein Name
Signal peptidase complex subunit 2 (Microsomal signal peptidase 25 kDa subunit) (SPase 25 kDa subunit)
Other Name
Species
Human
Gene ID
9789
Uniprot
Q15005,
Species.1
Mouse
Gene ID.1
66624
Uniprot.1
Q9CYN2
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Endoplasmic reticulum membrane; Multi-pass membrane protein .
Tissue Expression
Signaling_pathway
Research Areas
Function
Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum . Enhances the enzymatic activity of SPC and facilitates the interactions between different components of the translocation site (By similarity).