Name: SPRY3 rabbit pAb
SKU: WP8602
Price: 268 USD
Availability: InStock

SPRY3 rabbit pAb

Ucallm_WP8602-50

Price range: $268.00 through $328.00

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SKU: WP8602-100

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Product details

Background:

Specifications

Size	50μL/100μL
Target	SPRY3
Reactivity	Human
Applications	WB
MW(Calculated)	32kD
MW(Observed)
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-2000
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from human SPRY3
Specificity	This antibody detects endogenous levels of SPRY3 at Human
Gene Name	SPRY3
Protein Name	Protein sprouty homolog 3 (Spry-3)
Other Name
Species	Human
Gene ID	10251
Uniprot	O43610
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Cytoplasm.
Tissue Expression	Widely expressed; particularly in the fetal tissues. Expressed in the brain with expression the highest in Purkinje cells in the cerebellum (at protein level) (PubMed:26089202). Expressed in the myocardium of the heart (PubMed:30878395).
Signaling_pathway
Research Areas
Function	Inhibits neurite branching, arbor length and neurite complexity (By similarity). Inhibits EGF-mediated p42/44 ERK signaling (By similarity). Negatively regulates the MAPK cascade, resulting in a reduction of extracellular matrix protein accumulation . May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis .

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