SKU: WP7144 Categories: ,

SUNC1 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP7144-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetSUN3
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)39kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human SUNC1
SpecificityThis antibody detects endogenous levels of SUNC1 at Human, Mouse
Gene NameSUN3 SUNC1
Protein NameSUN domain-containing protein 3 (Sad1/unc-84 domain-containing protein 1)
Other Name
SpeciesHuman
Gene ID256979
UniprotQ8TAQ9,
Species.1Mouse
Gene ID.1194974
Uniprot.1Q5SS91
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationMembrane; Single-pass membrane protein . Nucleus envelope . Nucleus inner membrane .
Tissue Expression
Signaling_pathway
Research Areas
FunctionAs a probable component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex, involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. May be involved in nuclear remodeling during sperm head formation in spermatogenenis. A probable SUN3:SYNE1 LINC complex may tether spermatid nuclei to posterior cytoskeletal structures such as the manchette.
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