SUV3 rabbit pAb
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | SUV3 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA, IHC |
| MW(Calculated) | 86kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human SUV3 AA range: 443-493 |
| Specificity | This antibody detects endogenous levels of SUV3 at Human/Mouse/Rat |
| Gene Name | SUPV3L1 SUV3 |
| Protein Name | SUV3 |
| Other Name | |
| Species | Human |
| Gene ID | 6832 |
| Uniprot | Q8IYB8, |
| Species.1 | Mouse |
| Gene ID.1 | 338359 |
| Uniprot.1 | Q80YD1, |
| Species.2 | Rat |
| Gene ID.2 | 294385 |
| Uniprot.2 | Q5EBA1 |
| Cellular Localization | Nucleus . Mitochondrion matrix . Mitochondrion matrix, mitochondrion nucleoid . |
| Tissue Expression | Broadly expressed. |
| Signaling_pathway | |
| Research Areas | |
| Function | cofactor:Magnesium or manganese.,enzyme regulation:Helicase activity toward DNA substrate is inhibited by micromolar concentrations of 5,6-dichloro-1-(beta-D-ribofuranosyl)benzotriazole (DRBT) and 4,5,6,7-tetrabromobenzotriazole (TBBT). Helicase activity toward RNA substrate is inhibited by elevated concentrations of TBBT. Inhibited by some ring-expanded nucleoside analogs.,Function:ATPase and DNA/RNA helicase able to unwind DNA/DNA, DNA/RNA and RNA/RNA duplexes in the 5'-3' direction. May protect cells from apoptosis.,similarity:Belongs to the helicase family.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,subunit:Interacts with HBXIP.,tissue specificity:Broadly expressed., |
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