SYAC rabbit pAb
Ucallm_WP3685-50
Price range: $268.00 through $328.00
Product details
Background:
The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | SYAC |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | |
| MW(Observed) | 105kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human SYAC AA range: 504-554 |
| Specificity | This antibody detects endogenous levels of SYAC at Human/Mouse/Rat |
| Gene Name | AARS |
| Protein Name | SYAC |
| Other Name | Alanine--tRNA ligase, cytoplasmic; / Alanyl-tRNA synthetase; / AlaRS; / Renal carcinoma antigen NY-REN-42 |
| Species | Human |
| Gene ID | 16 |
| Uniprot | P49588, |
| Species.1 | Mouse |
| Gene ID.1 | 234734 |
| Uniprot.1 | Q8BGQ7, |
| Species.2 | Rat |
| Gene ID.2 | 292023 |
| Uniprot.2 | P50475 |
| Cellular Localization | Cytoplasm . |
| Tissue Expression | Epithelium,Liver,Osteosarcoma,Placenta,Renal cell carcinoma, |
| Signaling_pathway | |
| Research Areas | >>Aminoacyl-tRNA biosynthesis |
| Function | Catalytic activity:ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala).,similarity:Belongs to the class-II aminoacyl-tRNA synthetase family.,subunit:Monomer., |
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