Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human SYCE1
Specificity
This antibody detects endogenous levels of SYCE1 at Human, Mouse,Rat
Gene Name
SYCE1 C10orf94
Protein Name
Synaptonemal complex central element protein 1 (Cancer/testis antigen 76) (CT76)
Other Name
Species
Human
Gene ID
93426
Uniprot
Q8N0S2,
Species.1
Mouse
Gene ID.1
74075
Uniprot.1
Q9D495,
Species.2
Rat
Gene ID.2
502372
Uniprot.2
Q5XHZ2
Cellular Localization
Nucleus . Chromosome . Associates with chromatin. In prophase I stage of meiosis, localizes in the transverse central elements of the central region between lateral elements of the synaptonemal complexes. Found only where the chromosome cores are synapsed. Colocalizes with SYCE2 in the central elements. .
Tissue Expression
Signaling_pathway
Research Areas
Function
Major component of the transverse central element of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Requires SYCP1 in order to be incorporated into the central element. May have a role in the synaptonemal complex assembly, stabilization and recombination.