Price range: $268.00 through $328.00
Background:
This gene encodes a protein that transfers phenylalanine to its cognate tRNA. This protein localizes to the mitochondrion and plays a role in mitochondrial protein translation. Mutations in this gene can cause combined oxidative phosphorylation deficiency 14 (Alpers encephalopathy). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
| Size | 50μL/100μL |
| Target | SYFM |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA, IHC |
| MW(Calculated) | 50kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human SYFM AA range: 294-344 |
| Specificity | This antibody detects endogenous levels of SYFM at Human/Mouse/Rat |
| Gene Name | FARS2 FARS1 HSPC320 |
| Protein Name | SYFM |
| Other Name | |
| Species | Human |
| Gene ID | 10667 |
| Uniprot | O95363, |
| Species.1 | Mouse |
| Gene ID.1 | 69955 |
| Uniprot.1 | Q99M01, |
| Species.2 | Rat |
| Gene ID.2 | 306879 |
| Uniprot.2 | Q6AYQ3 |
| Cellular Localization | Mitochondrion matrix . Mitochondrion . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | >>Aminoacyl-tRNA biosynthesis |
| Function | Catalytic activity:ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe).,similarity:Belongs to the class-II aminoacyl-tRNA synthetase family.,similarity:Contains 1 FDX-ACB domain.,subunit:Monomer., |
