Price range: $268.00 through $328.00
Background:
This gene encodes a subunit of the RNA polymerase I complex, Selectivity Factor I (SLI). The encoded protein is a TATA box-binding protein-associated factor that plays a role in the assembly of the RNA polymerase I preinitiation complex. Alternate splicing results in multiple transcript variants encoding multiple isoforms.[provided by RefSeq, Jan 2011],
| Size | 50μL/100μL |
| Target | TAF I p48 |
| Reactivity | Human, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 53kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human TAF1A. AA range:301-350 |
| Specificity | TAF I p48 Polyclonal Antibody detects endogenous levels of TAF I p48 protein. |
| Gene Name | TAF1A |
| Protein Name | TATA box-binding protein-associated factor RNA polymerase I subunit A |
| Other Name | TAF1A; / TATA box-binding protein-associated factor RNA polymerase I subunit A; / RNA polymerase I-specific TBP-associated factor 48 kDa; / TAFI48; / TATA box-binding protein-associated factor 1A; / TBP-associated factor 1A; / Transcription factor SL1 |
| Species | Human |
| Gene ID | 9015 |
| Uniprot | Q15573, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P97357, |
| Species.2 | Rat |
| Gene ID.2 | 360893 |
| Uniprot.2 | Q3B7U2 |
| Cellular Localization | Nucleus. |
| Tissue Expression | Embryo,Skin, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Component of the transcription factor SL1/TIFIB complex involved in the assembly of the PIC (preinitiation complex).,subunit:Component of the transcription factor SL1/TIFIB complex which is composed of TBP and at least TAF1A, TAF1B and TAF1C. In the complex, interacts directly with TBP, TAF1B and TAF1C. Interaction of the SL1/TIFIB subunits with TBP excludes interaction with the transcription factor IID (TFIID) subunits. This mutually exclusive binding directs the formation of promoter and RNA polymerase-selective TBP-TAF complexes., |
