Product details
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TCP11 rabbit pAb
Ucallm_WP7942-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | TCP11 |
| Reactivity | Human, Rat |
| Applications | WB |
| MW(Calculated) | 55kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TCP11 |
| Specificity | This antibody detects endogenous levels of TCP11 at Human,Rat |
| Gene Name | TCP11 |
| Protein Name | T-complex protein 11 homolog |
| Other Name | |
| Species | Human |
| Gene ID | 6954 |
| Uniprot | Q8WWU5, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q01755, |
| Species.2 | Rat |
| Gene ID.2 | 309641 |
| Uniprot.2 | Q5XI00 |
| Cellular Localization | Membrane; Single-pass membrane protein . Cell projection, cilium, flagellum . Cytoplasmic vesicle, secretory vesicle, acrosome . Localizes on the acrosomal cap region of acrosome-intact, but not acrosome-reacted sperm. Colocalizes with MROH2B and PRKACA on the acrosome and tail regions in round spermatids and spermatozoa regardless of the capacitation status of the sperm. . |
| Tissue Expression | Isoform 2 and isoform 3 are expressed in sperm. Isoform 1 is not detected in sperm (at protein level) (PubMed:21597245). Testis-specific (PubMed:11756566). Isoform 1, isoform 2 and isoform 3 are expressed in sperm (PubMed:21597245). |
| Signaling_pathway | |
| Research Areas | |
| Function | Plays a role in the process of sperm capacitation and acrosome reactions. Probable receptor for the putative fertilization-promoting peptide (FPP) at the sperm membrane that may modulate the activity of the adenylyl cyclase cAMP pathway. |
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