SKU: WP8129 Categories: ,

TDRD5 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP8129-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetTDRD5
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)108kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human TDRD5
SpecificityThis antibody detects endogenous levels of TDRD5 at Human, Mouse,Rat
Gene NameTDRD5
Protein NameTudor domain-containing protein 5
Other Name
SpeciesHuman
Gene ID163589
UniprotQ8NAT2,
Species.1Mouse
Gene ID.1214575
Uniprot.1Q5VCS6,
Species.2Rat
Gene ID.2289129
Uniprot.2B4F7C4
Cellular LocalizationCytoplasm . Localizes to chromatoid body (CB) and pi-body (also called intermitochondrial cementin), 2 cytoplasmic ribonucleoprotein granules involved in RNA processing for spermatogenesis. .
Tissue Expression
Signaling_pathway
Research Areas
FunctionRequired during spermiogenesis to participate in the repression transposable elements and prevent their mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB) assembly (By similarity).
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