TFIP11 is a nuclear speckle-localized protein that may play a role in spliceosome disassembly in Cajal bodies (Stanek et al., 2008 [PubMed 18367544]).[supplied by OMIM, Apr 2009],
Specifications
Size
50μL/100μL
Target
TFP11
Reactivity
Human, Mouse, Rat
Applications
WB
MW(Calculated)
92kD
MW(Observed)
Host Species
Rabbit
Isotype
IgG
Conjugate/Modification
Unmodified
Recommended Dilution Ratio
WB 1:500-2000
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human TFP11 AA range: 210-260
Specificity
This antibody detects endogenous levels of TFP11 at Human/Mouse/Rat
Gene Name
TFIP11 STIP HSPC006
Protein Name
TFP11
Other Name
Species
Human
Gene ID
24144
Uniprot
Q9UBB9,
Species.1
Mouse
Gene ID.1
54723
Uniprot.1
Q9ERA6,
Species.2
Rat
Gene ID.2
288718
Uniprot.2
Q5U2Y6
Cellular Localization
Cytoplasm . Nucleus . In the nucleus localizes to unique speckle domains in close proximity to nuclear speckles and not identical to paraspeckles. .
Tissue Expression
Signaling_pathway
Research Areas
Function
Function:May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extracellular matrix. May also be involved in pre-mRNA splicing.,similarity:Belongs to the TFP11/STIP family.,similarity:Contains 1 G-patch domain.,subunit:Interacts with TUFT1 (By similarity). Identified in the spliceosome C complex, at least composed of AQR, ASCC3L1, C19orf29, CDC40, CDC5L, CRNKL1, DDX23, DDX41, DDX48, DDX5, DGCR14, DHX35, DHX38, DHX8, EFTUD2, FRG1, GPATC1, HNRPA1, HNRPA2B1, HNRPA3, HNRPC, HNRPF, HNRPH1, HNRPK, HNRPM, HNRPR, HNRPU, KIAA1160, KIAA1604, LSM2, LSM3, MAGOH, MORG1, PABPC1, PLRG1, PNN, PPIE, PPIL1, PPIL3, PPWD1, PRPF19, PRPF4B, PRPF6, PRPF8, RALY, RBM22, RBM8A, RBMX, SART1, SF3A1, SF3A2, SF3A3, SF3B1, SF3B2, SF3B3, SFRS1, SKIV2L2, SNRPA1, SNRPB, SNRPB2, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF, SNRPG, SNW1, SRRM1, SRRM2, SYF2, SYNCRIP, TFIP11, THOC4, U2AF1, WDR57, XAB2 and ZCCHC8.,