Price range: $268.00 through $328.00
Background:
The protein encoded by this gene contains a THAP domain, which is a conserved DNA-binding domain that has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases. [provided by RefSeq, Jul 2008],
| Target | THAP11 |
| Reactivity | Human |
| Applications | WB, IHC, IF, FC, ELISA |
| MW(Calculated) | 34kD |
| MW(Observed) | |
| Host Species | Mouse |
| Isotype | |
| Conjugate/Modification | Unmodified |
| Modification | |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; Flow Cyt 1:200-1:400; ELISA 1:10000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#YS0004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Source | |
| Purification | Affinity purification |
| Purity | |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | 200 |
| Immunogen | Purified recombinant fragment of human THAP11 expressed in E. Coli. |
| Sequence | |
| Specificity | THAP11 Monoclonal Antibody detects endogenous levels of THAP11 protein. |
| Gene Name | THAP11 |
| Protein Name | THAP domain-containing protein 11 |
| Other Name | THAP11; / HRIHFB2206; / THAP domain-containing protein 11 |
| Species | Human |
| Gene ID-1 | 57215 |
| Uniprot | Q96EK4, |
| Species.1 | Mouse |
| Gene ID-2 | |
| Uniprot.1 | Q9JJD0 |
| Species.2 | |
| Gene ID-3 | |
| Uniprot.2 | |
| Organism-4 | |
| Gene ID-4 | |
| SwissProt-4 | |
| Background | The protein encoded by this gene contains a THAP domain, which is a conserved DNA-binding domain that has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases. [provided by RefSeq, Jul 2008], |
| Cellular Localization | Nucleus . Cytoplasm . May be regulated by shuttling of the protein between the cytoplasm and nucleus. . |
| Tissue Expression | Brain,Neuroblastoma,Uterus, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers.,polymorphism:The length of the poly-Gln region is variable in the population.,similarity:Belongs to the THAP11 family.,similarity:Contains 1 THAP-type zinc finger.,subcellular location:May be regulated by shuttling of the protein between the cytoplasm and nucleus.,subunit:Interacts (via coiled coil domain) with HCFC1., |
| RRID |
