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TIG1 Polyclonal Antibody
Ucallm_WP16064-50
Price range: $268.00 through $328.00
Product details
Background:
This gene was identified as a retinoid acid (RA) receptor-responsive gene. It encodes a type 1 membrane protein. The expression of this gene is upregulated by tazarotene as well as by retinoic acid receptors. The expression of this gene is found to be downregulated in prostate cancer, which is caused by the methylation of its promoter and CpG island. Alternatively spliced transcript variant encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | TIG1 |
| Reactivity | Human |
| Applications | IHC, IF, WB |
| MW(Calculated) | |
| MW(Observed) | 51kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:50-200; WB 1:500-2000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human TIG1 |
| Specificity | This antibody detects endogenous levels of human TIG1 |
| Gene Name | RARRES1 TIG1 |
| Protein Name | TIG1 |
| Other Name | Retinoic acid receptor responder protein 1; / RAR-responsive protein TIG1; / Tazarotene-induced gene 1 protein |
| Species | Human |
| Gene ID | 5918 |
| Uniprot | P49788 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Membrane; Single-pass type III membrane protein . |
| Tissue Expression | Skin, |
| Signaling_pathway | |
| Research Areas | |
| Function | induction:By tazarotene and by all the retinoic acid receptors tested.,similarity:Belongs to the protease inhibitor I47 (latexin) family., |
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