TLX3 Polyclonal Antibody
Product details
Background:
The protein encoded by this gene is an orphan homeobox protein that encodes a DNA-binding nuclear transcription factor. A translocation [t(5;14)(q35;q32)] involving this gene is associated with T-cell acute lymphoblastic leukemia (T-ALL) in children and young adults. [provided by RefSeq, Nov 2015],
Specifications
| Size | 50μL/100μL |
| Target | TLX3 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 32kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | TLX3 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | TLX3 HOX11L2 |
| Protein Name | T-cell leukemia homeobox protein 3 (Homeobox protein Hox-11L2) |
| Other Name | |
| Species | Human |
| Gene ID | 30012 |
| Uniprot | O43711, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | O55144 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Muscle, |
| Signaling_pathway | Human Diseases >> Cancer: overview >> Transcriptional misregulation in cancer |
| Research Areas | >>Transcriptional misregulation in cancer |
| Function | similarity:Contains 1 homeobox DNA-binding domain., |
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